SERVE - Socio-Economic Value of Respiratory Vaccination: Evaluation for Adults

We are conducting the empirical study SERVE – Socio-Economic Value of Respiratory Vaccination: Evaluation for Swiss Adults. SERVE has been commissioned by a consortium of key stakeholders in Switzerland.

Factsheet

  • Schools involved School of Health Professions
  • Institute(s) Institute of Health Economics and Health Policy
  • Strategic thematic field Thematic field "Caring Society"
  • Funding organisation Others
  • Duration (planned) 01.08.2025 - 31.08.2027
  • Head of project Niklaus Meier
  • Project staff Prof. Dr. Katharina Blankart
    Daniel Ammann
  • Partner GaleniCare Management AG
    Genossenschaft KPT
    GlaxoSmithKline AG
    Moderna Switzerland GmbH
    MSD Merck Sharp & Dohme AG
    Pfizer AG Zürich
    Sanofi-Aventis (Suisse) SA
    Pharmasuisse
    Stiftung Sanitas

Situation

Vaccination can generate substantial benefits across multiple dimensions of health care, including reduced mortality, improved quality of life, lower health care utilization, and increased economic productivity. Despite these well-documented benefits and the broad availability of vaccines, uptake remains suboptimal in certain disease areas, particularly for common respiratory diseases and among adults. To support informed decision-making, there is a need for robust evidence on the magnitude of these health and economic effects in the Swiss context. Such information is essential for the general population, the health care system, and policymakers.

Course of action

The aim of SERVE is to assess the potential socio-economic value of increasing vaccination coverage among Swiss adults for four respiratory diseases: influenza, respiratory syncytial virus (RSV), pneumococcal disease, and endemic COVID-19. This research project brings together a great deal of expertise from academia as well as the SERVE consortium. By combining this interdisciplinary expertise with innovative methods from health economics and epidemiology, SERVE seeks to generate new evidence on a complex and policy-relevant topic.

Result

For each included disease, we will estimate the burden of illness, including vaccination costs, health care expenditures, and adverse health outcomes. In addition, we will assess productivity losses associated with illness and quantify the potential productivity gains for employers resulting from vaccination programs that reduce infections among the workforce. Using epidemiological transmission models, we will evaluate the overall impact of higher adult vaccination rates on disease burden and productivity. Considering vaccination costs (including vaccines and administration) and changes in health and economic outcomes, we will estimate the return on investment (ROI) per Swiss franc invested in adult vaccination for each disease.

Looking ahead

We are currently developing a detailed study protocol for SERVE, which will be published in a peer-reviewed journal. Based on this protocol, we will conduct the SERVE study and publish the results, along with non-confidential data, as open-access resources. All rights to the research findings will be placed in the public domain, and all methods used or developed within SERVE will be published as open source. We will communicate the summarized results of SERVE to a broader audience through concise and accessible policy briefs.

SERVE – Socio-Economic Value of Respiratory Vaccination: Evaluation for Swiss Adults
SERVE – Socio-Economic Value of Respiratory Vaccination: Evaluation for Swiss Adults

This project contributes to the following SDGs

  • 3: Good health and well-being
  • 8: Decent work and economic growth